# Complete genome sequence of Pseudomonas sp. PP3, a dehalogenase-producing bacterium, confirms the unusual mobile genetic element DEH

**Authors:** Gordon Webster, Amy J. Baldwin, Edward Cunningham-Oakes, Alex J. Mullins, Rachel Dodds, Katja E. Hill, Li Ling Lee, Mark J. Leggett, Andrew W. Topping, Andrew J. Weightman

PMC · DOI: 10.1128/mra.00089-25 · Microbiology Resource Announcements · 2025-04-21

## TL;DR

The genome of Pseudomonas sp. PP3, a bacterium that breaks down harmful chemicals, was fully sequenced and shows it is closely related to P. reinekei.

## Contribution

The paper confirms the presence of the unusual mobile genetic element DEH in the genome of Pseudomonas sp. PP3.

## Key findings

- The genome of Pseudomonas sp. PP3 is 6.42 Mb in size.
- The genome is most closely related to P. reinekei.
- The bacterium produces dehalogenase, which is important for bioremediation.

## Abstract

Pseudomonas sp. PP3, originally isolated from contaminated soil enriched in a chemostat culture on 2,2-dichloropropionic acid, has a 6.42 Mb genome, most closely related to P. reinekei. This well-characterized organism continues to provide key insights into adaptive dehalogenase-mediated bioremediation of halogenated organic pollutants.

## Linked entities

- **Chemicals:** 2,2-dichloropropionic acid (PubChem CID 6418)
- **Species:** Pseudomonas sp. PP3 (taxon 2815936)

## Full-text entities

- **Chemicals:** 2,2-dichloropropionic acid (MESH:C004743), PP3 (-)
- **Species:** Pseudomonas sp. (species) [taxon 306], Pseudomonas reinekei (species) [taxon 395598]

## Full text

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## Figures

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## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12060670/full.md

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Source: https://tomesphere.com/paper/PMC12060670