# How to take action beyond ambulatory glucose profile: Latin American expert recommendations on CGM data interpretation

**Authors:** Luis Eduardo Calliari, Álvaro Contreras Sepúlveda, Nicolás Coronel-Restrepo, Laura Kabakian, Rodrigo N. Lamounier, Emma Picasso, Adrian Proietti, Alex Ramírez-Rincón, Alicia E. Yépez-Rodriguez

PMC · DOI: 10.1186/s13098-025-01702-y · Diabetology & Metabolic Syndrome · 2025-05-08

## TL;DR

Experts in Latin America provide guidelines for interpreting continuous glucose monitoring data to improve diabetes care and address regional healthcare challenges.

## Contribution

A standardized, regionally adapted methodology for CGM data interpretation in Latin America.

## Key findings

- Reliable CGM interpretation requires at least 70% sensor use over 14 days.
- The AGP report provides key metrics like TIR, TBR, TAR, CV, and GMI for personalized diabetes management.
- Standardized CGM interpretation can improve glycemic control and reduce healthcare disparities in the region.

## Abstract

This expert consensus provides a standardized methodology for interpreting continuous glucose monitoring (CGM) data to optimize diabetes management. It aims to help healthcare professionals recognize glycemic patterns and apply targeted interventions based on real-time glucose metrics.

A systematic literature review informed expert panel discussions. Specialists from Latin America assessed CGM interpretation challenges, reviewed key metrics, and reached consensus through an anonymous voting process. The recommendations align with international guidelines while addressing regional limitations in technology access and healthcare infrastructure.

Reliable CGM data interpretation requires at least 70% sensor use over 14 days. The Ambulatory Glucose Profile (AGP) report serves as the primary tool, offering essential metrics such as time in range (TIR), time below range (TBR), time above range (TAR), coefficient of variation (CV), and glucose management indicator (GMI). Identifying hyperglycemia, hypoglycemia, and glucose variability allows for personalized treatment adjustments. The panel adopted international glycemic targets, adapting them to Latin American settings. The time in tight range (TITR) was considered but not included due to limited supporting evidence and regional barriers to advanced CGM technology.

Standardized CGM interpretation improves glycemic control and treatment decisions. These recommendations provide a structured approach to diabetes care, aiming to enhance clinical outcomes and address healthcare disparities in Latin America.

The online version contains supplementary material available at 10.1186/s13098-025-01702-y.

## Linked entities

- **Diseases:** diabetes (MONDO:0005015)

## Full-text entities

- **Diseases:** hypoglycemia (MESH:D007003), diabetes (MESH:D003920), hyperglycemia (MESH:D006943)

## Full text

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## Figures

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## References

4 references — full list in the complete paper: https://tomesphere.com/paper/PMC12060294/full.md

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Source: https://tomesphere.com/paper/PMC12060294