# Non-use of dentures after tooth loss is associated with elevated sodium/potassium ratios in older adults: a retrospective cohort study

**Authors:** Takafumi Abe, Tsuyoshi Hamano, Haruki Usuda, Koichiro Wada, Kenta Okuyama, Kazumichi Tominaga, Shozo Yano, Minoru Isomura

PMC · DOI: 10.3389/fdmed.2025.1479896 · Frontiers in Dental Medicine · 2025-04-24

## TL;DR

Older adults who don't use dentures after losing many teeth have higher sodium-to-potassium ratios, which can increase hypertension risk.

## Contribution

This study is the first to show that denture use may mitigate changes in the Na/K ratio after tooth loss in older adults.

## Key findings

- Non-denture users with 0–19 teeth had a significant increase in the Na/K ratio.
- Denture users with 0–19 teeth did not show a significant change in the Na/K ratio.
- Promoting denture use could help maintain a healthy Na/K balance in older adults with tooth loss.

## Abstract

An elevated sodium-to-potassium (Na/K) ratio in urine increases the risk of hypertension. Tooth loss in older adults can lead to a diminished nutritional state, including alterations in the Na/K ratio. However, the relationship between denture use and changes in the Na/K ratio among individuals with tooth loss has not been sufficiently explored. This study examined whether denture use modifies the association between tooth loss and changes in the Na/K ratio.

Surveys in 2016 and 2018 included 473 older adults. The Na/K ratio was measured using spot urine tests. A dental hygienist evaluated the number of teeth and the use of dentures. We used generalized linear models to analyze the combined effect of the number of teeth and denture use on changes in the Na/K ratio.

Participants without dentures in the 0–19 teeth group showed a significant association with changes in the Na/K ratio (B = 0.635; 95% confidence interval = 0.038, 1.232) compared to those with ≥28 teeth, but denture users with 0–19 teeth did not show significant association. No significant association with changes in the Na/K ratio was observed in denture users and non-users with 20–27 teeth.

In non-denture users with fewer than 20 teeth, the Na/K ratio was markedly elevated, but in denture users with fewer than 20 teeth it was not significant. These findings highlight the importance of promoting denture use in older adults with few remaining teeth to maintain their Na/K balance.

## Linked entities

- **Chemicals:** sodium (PubChem CID 5360545), potassium (PubChem CID 813)

## Full-text entities

- **Diseases:** Tooth loss (MESH:D016388), hypertension (MESH:D006973)
- **Chemicals:** Na (MESH:D012964), K (MESH:D011188)

## Full text

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## Figures

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## References

40 references — full list in the complete paper: https://tomesphere.com/paper/PMC12058787/full.md

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Source: https://tomesphere.com/paper/PMC12058787