# Editorial: The role of ubiquitination in disease development, progression, and prognosis

**Authors:** Mingyang Xue, Wenyi Jin

PMC · DOI: 10.3389/fimmu.2025.1595755 · Frontiers in Immunology · 2025-04-24

## Full-text entities

- **Genes:** NFKB1 (nuclear factor kappa B subunit 1) [NCBI Gene 4790] {aka CVID12, EBP-1, KBF1, NF-kB, NF-kB1, NF-kappa-B1}, STING1 (stimulator of interferon response cGAMP interactor 1) [NCBI Gene 340061] {aka ERIS, MITA, MPYS, NET23, SAVI, STING}, STAT1 (signal transducer and activator of transcription 1) [NCBI Gene 6772] {aka CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91}, BIRC3 (baculoviral IAP repeat containing 3) [NCBI Gene 330] {aka AIP1, API2, CIAP2, HAIP1, HIAP1, IAP-1}, CCL2 (C-C motif chemokine ligand 2) [NCBI Gene 6347] {aka GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1}, RIPK1 (receptor interacting serine/threonine kinase 1) [NCBI Gene 8737] {aka AIEFL, IMD57, RIP, RIP-1, RIP1}, NLRP3 (NLR family pyrin domain containing 3) [NCBI Gene 114548] {aka AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1}, CGAS (cyclic GMP-AMP synthase) [NCBI Gene 115004] {aka C6orf150, D4, MB21D1, h-cGAS}
- **Diseases:** steatohepatitis (MESH:D005234), autoimmune (MESH:D001327), neurological diseases (MESH:D020271), metabolic disorders (MESH:D008659), chronic inflammation (MESH:D007249), pain (MESH:D010146), cancer (MESH:D009369), neuroinflammation (MESH:D000090862), inflammatory bowel disease (MESH:D015212), gastrointestinal cancers (MESH:D005770), hepatocellular carcinoma (MESH:D006528), migraine (MESH:D008881), Sepsis (MESH:D018805), RA (MESH:D001172), chronic viral hepatitis (MESH:D006525), joint damage (MESH:D007592)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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Source: https://tomesphere.com/paper/PMC12058771