# Impact of Educational Interventions on the Quality of Life of Patients With Stage 4-5 Chronic Kidney Disease

**Authors:** Marianna A Eleftheroudi, Efstathios Mitsopoulos, Dorothea Papadopoulou, Gerasimos Bamichas, Apostolos Kyrgialanis, Fani Papoulidou, Elias Thodis, Maria Samakouri, Stylianos Panagoutsos, Ploumis Passadakis

PMC · DOI: 10.7759/cureus.81839 · 2025-04-07

## TL;DR

This study shows that educational interventions can improve the quality of life and mental health of patients with advanced kidney disease.

## Contribution

The study introduces a tailored educational intervention and evaluates its impact on psychological and social outcomes in CKD patients.

## Key findings

- Higher satisfaction with the intervention was linked to reduced anxiety and depression.
- Satisfaction also correlated with improved social functioning and psychological resilience.
- Tailoring the intervention to individual patient needs may enhance its effectiveness.

## Abstract

Background and objectives

Chronic kidney disease (CKD) and its management can adversely affect patients' quality of life and mental health. Many patients are often inadequately informed about their condition and the available treatment options. A considerable number of people with advanced kidney disease have insufficient knowledge about their condition and the available treatment options. This study aims to investigate the impact of an educational intervention on quality of life, psychological resilience, anxiety, and depression. This study specifically aims to evaluate the effectiveness of this intervention on variables such as quality of life, psychological resilience, anxiety, and depression.

Methods

A prospective randomized study was conducted on patients with CKD stage 4-5 to evaluate the effectiveness of an educational intervention in improving the aforementioned parameters. Furthermore, the correlation between these outcomes and the level of satisfaction with the intervention was analyzed. Participants were randomized (3:1) into two groups: an educational intervention group (33 patients) and a control group (12 patients). In the intervention group, we performed educational presentations accompanied by a relevant video. Participants completed the questionnaires both before and after the intervention. Participants in the control group were only asked to complete the questionnaires again after the same time period as the intervention group.

Results

Higher satisfaction with the intervention was significantly associated with a reduction in anxiety (r = -0.38, p = 0.03) and depression scores (r = -0.44, p = 0.01), along with a notable improvement in social functioning (r = 0.40, p = 0.02). Furthermore, a marginally significant positive correlation was observed between the satisfaction scale and psychological resilience (r = 0.32, p = 0.07).

Conclusion

The level of satisfaction with the intervention is a critical factor in determining its effectiveness. Tailoring the intervention to address the unique needs of each patient may significantly enhance its impact.

## Linked entities

- **Diseases:** Chronic kidney disease (MONDO:0005300)

## Full-text entities

- **Diseases:** CKD (MESH:D051436), anxiety (MESH:D001007), kidney disease (MESH:D007674), depression (MESH:D003866)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC12057799