# Massive Scrotal Lymphedema in an Adolescent with Intellectual Disability: A Rare Case of Infection-Related Scrotal Enlargement Requiring Subtotal Scrotectomy

**Authors:** Muhammad Saqlain, Masood Ur-Rauf Khan Hiraj, Muhammad Ans, Muhammad Usama Ilyas Ahmed

PMC · DOI: 10.7759/cureus.81821 · 2025-04-07

## TL;DR

A 17-year-old with intellectual disability had severe scrotal lymphedema due to infection, treated with surgery to improve mobility and hygiene.

## Contribution

Presents a rare case of infection-related scrotal lymphedema managed with subtotal scrotectomy in an adolescent with intellectual disability.

## Key findings

- Severe scrotal lymphedema in an adolescent was successfully treated with subtotal scrotectomy.
- Histopathology showed chronic inflammation without filarial involvement, suggesting infection as the cause.
- Postoperative recovery improved mobility and hygiene in the patient.

## Abstract

An uncommon disorder marked by aberrant fluid accumulation brought on by lymphatic blockage, scrotal lymphedema presents major functional, cosmetic, and hygiene problems. It can be acquired or congenital; the most often occurring causes are infection, persistent inflammation, and filariasis. This case report describes a 17-year-old male patient with intellectual disability who had severe scrotal lymphedema that gradually developed over four years, causing problems with ambulation and hygienic care. Under a clinical examination, the scrotum (40 x 15 cm) was swollen and expanded, hiding the penis but having palpable testes. Ultrasound verified without testicular involvement scrotal wall thickening. After a subtotal scrotectomy preserves the testes, penis, and spermatic cord, scrotal reconstruction was done considering the functional limitation. Chronic inflammatory alterations without filarial organisms revealed by histopathology suggested an etiology connected to infections. The patient healed postoperatively with better mobility and hygienic standards. This example emphasizes the need for early identification and surgical intervention in controlling large scrotal lymphedema to maximize functional and cosmetic results.

## Linked entities

- **Diseases:** intellectual disability (MONDO:0001071)

## Full-text entities

- **Diseases:** filariasis (MESH:D005368), Infection (MESH:D007239), Intellectual Disability (MESH:D008607), Scrotal Lymphedema (MESH:D008209), inflammation (MESH:D007249)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12056880/full.md

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Source: https://tomesphere.com/paper/PMC12056880