# Congenitally corrected transposition of the great arteries: one disease, diverse manifestations—a case series

## TL;DR

This paper presents four cases of a rare heart defect called congenitally corrected transposition of the great arteries, highlighting the varied symptoms and challenges in diagnosis and treatment.

## Contribution

The paper contributes a case series that emphasizes the use of multimodal imaging and the management challenges across the lifespan in patients with ccTGA.

## Key findings

- Multimodality imaging is crucial for diagnosing and managing ccTGA.
- ccTGA patients face long-term complications like arrhythmias and heart failure.
- Pregnancy and acquired heart disease add complexity to managing ccTGA.

## Abstract

Congenitally corrected transposition of the great arteries (ccTGA) is a rare congenital heart defect with heterogenous clinical manifestations that can pose both diagnostic and management challenges throughout life.

We describe four patients with ccTGA and different presentations including sudden cardiac arrest, progressive heart failure, post-partum heart failure, and NSTEMI.

This case series aims to illustrate the importance of multimodality imaging to assist the diagnosis and support treatment strategies in patients with ccTGA. Direct long-term sequalae, such as arrythmias and heart failure, and the associated management challenges are highlighted. Additionally, the challenges of managing pregnancy with a sRV and the development of acquired heart disease demonstrate the clinical care challenges in caring for this population across the life span.