# Effectiveness screening of SARS-CoV-2 (COVID-19) in the municipality of Andratx (Balearic Islands, Spain)

## TL;DR

This study evaluated SARS-CoV-2 infection rates and immune responses in essential and non-essential workers and their children in Andratx, Spain, finding that control measures were effective.

## Contribution

The study provides localized data on SARS-CoV-2 prevalence and immune responses in essential and non-essential workers in a specific Spanish municipality.

## Key findings

- Non-essential workers showed higher antibody levels compared to essential workers during certain periods.
- Control measures in Andratx were found to be effective in managing the pandemic.
- Children of essential workers had a higher percentage of positive antibody tests than children of non-essential workers.

## Abstract

The coronavirus disease 2019 (COVID-19) pandemic was a global health emergency that significantly affected both the wellbeing of individuals and the global economy.

The aim of this study was to evaluate the degree of SARS-CoV-2 involvement, viral load, and immunological response in adults aged 18–65 who performed essential tasks in the municipality of Andratx (Balearic Islands, Spain) compared to those who did not. Additionally, the study examined these factors in children aged 2–18 years from both groups, if there were any.

Both groups were monitored between July 2020 and February 2021, in which the degree of involvement, the viral load, and the immunological response to the SARS-CoV-2 were analyzed using questionnaires, polymerase chain reaction (PCR) tests, and ELISA serology tests.

A positive case of RT-PCR test was found in screening the general population. The highest 2019-nCoV(N)-Ig antibody levels in plasma were measured from 1 to 17 February 2021, with the following percentage of positives: 6.8% of essential workers, 9.5% of essential workers’ sons, 7.3% of non-essential workers, and 2.2% of non-essential workers’ sons. However, an increase in levels of anti-SARS-CoV-2 (N) immunoglobulin G (IgG) and anti-SARS-CoV-2 (N) immunoglobulin M (IgM) were produced in session 3, from 9 to 25 November 2020, in both cases in non-essential workers, with a mean of 218.1 ng/mL of anti-SARS-CoV-2 (N) IgG and 31.3 ng/mL of anti-SARS-CoV-2 (N) IgM.

The control measures taken to manage the COVID-19 pandemic in the municipality of Andratx, Mallorca, Spain, were effective.