# Lapdoctor: Multicentre Validation of a Scoring System for Preoperative Evaluation of Difficulty of Laparoscopic Donor Nephrectomy

**Authors:** Jacopo Romagnoli, Gionata Spagnoletti, Francesco Emilio Rossini, Roberto Iezzi, Alessandro Posa, Maria Paola Salerno, Patrizia Silvestri, Aldo Eugenio Rossini, Cristina Silvestre, Barbara Franchin, Alessandro Giacomoni, Leonardo Centonze, Marco Spada, Maurizio Iaria, Carmelo Puliatti, Lucrezia Furian

PMC · DOI: 10.3389/ti.2025.14100 · Transplant International · 2025-04-23

## TL;DR

The paper validates a scoring system called LAPDOCTOR to assess the difficulty of laparoscopic donor nephrectomy surgeries across multiple centers.

## Contribution

The LAPDOCTOR scoring system is prospectively validated in a multicenter study for preoperative evaluation of laparoscopic donor nephrectomy difficulty.

## Key findings

- LAPDOCTOR scores showed strong agreement with surgeon-assessed difficulty (QWK of 0.711).
- The system is effective in identifying very difficult cases and surgical risk for living kidney donors.

## Abstract

We previously developed and validated LAPDOCTOR (LAParoscopic-Donor-nephreCTomy-scORe), a novel scoring system for the preoperative assessment of the difficulty of living donor nephrectomy (LDN). To prove its significance, we extended our investigation to a prospective, multicenter, national study. Difficulty was assessed by the operating surgeon using a scale from 1 to 3 (1-standard, 2-moderately difficult, 3-very difficult) based on eight parameters: availability of laparoscopic space, mobilization of the colon, kidney, gonadal, adrenal and renal vein, renal artery, and ureter. Donor CT-scans were blindly reviewed by a radiologist, and the LAPDOCTOR scores were compared with the difficulty levels assigned by the surgeon to investigate the match rates. One hundred eighty-five donors were enrolled, with a mean age of 54 years (range 24–77), BMI 25 kg/m2 (range 17–35), and male/female 59/126. LDN was blindly scored as standard in 45% of the cases, moderately-difficult in 52%, and very-difficult in 3%. The agreement between the LAPDOCTOR and expert donor surgeons’ rate in categorizing LDN into risk groups had a QWK of 0.711 (95% CI 0.577–0.844) with p < 0.001. The LAPDOCTOR enables precise preoperative determination of the difficulty of LDN, particularly in very difficult cases, and assessment of surgical risk in living kidney donors.

https://ClinicalTrials.gov, Identifier NCT05769686.

## Full-text entities

- **Diseases:** blindness (MESH:D001766), obesity (MESH:D009765), renal vascular anomalies (MESH:C535986), drug abuse (MESH:D019966), respiratory or cardiovascular complications (MESH:D002318), infections with hepatitis B, hepatitis C (MESH:D006509), renal involvement (MESH:C565423), HIV (MESH:D015658), diabetes mellitus (MESH:D003920), blood (MESH:D006402), hypertension (MESH:D006973), pain (MESH:D010146), systemic diseases (MESH:D034721), thrombophilia (MESH:D019851), kidney diseases (MESH:D007674), organ damage (MESH:D000092124), infections (MESH:D007239), neoplasia (MESH:D009369)
- **Chemicals:** LDN (-)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12055550/full.md

## References

24 references — full list in the complete paper: https://tomesphere.com/paper/PMC12055550/full.md

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Source: https://tomesphere.com/paper/PMC12055550