# A Rare Case of Cystic Angiomatosis Involving the Bones: Our Experience and Review of Literature

**Authors:** Priyatesh Chandra Dwivedi, Chaitanya Borde, Ramesh Venkata Yasam, Raj Nagarkar

PMC · DOI: 10.1055/s-0044-1801385 · World Journal of Nuclear Medicine · 2025-01-09

## TL;DR

This paper reports a rare case of cystic angiomatosis in a young woman and highlights the importance of accurate diagnosis and treatment for this uncommon condition.

## Contribution

The paper contributes a rare clinical case of cystic angiomatosis involving bones and proposes zoledronic acid as a treatment option.

## Key findings

- A 24-year-old female was diagnosed with cystic angiomatosis involving bones and spleen.
- Zoledronic acid treatment was used to stabilize bone lesions in the patient.
- The paper emphasizes the need for more research on rare cases to improve understanding and treatment.

## Abstract

Cystic angiomatosis (CA) is a rare, benign, multifocal disorder of mixed lesions (lytic, sclerotic) developed due to maldeveloped lymphatic and vascular systems. In majority of cases, it is identified fortuitously and mimicked as metastatic malignant lesions. In such cases, differential diagnosis followed by treatment is identified to be critical for stabilizing the disease and its prognosis. We reported a case of a 24-year-old female who presented to our center with complaints of lower back ache (∼4–6 weeks), intermittent pain in the abdomen, and occasional dyspnea on exertion. Imaging studies revealed mild lytic lesions and small-sized cysts in the spine, bones, and spleen. Investigations confirmed CA and follow-up treatment was given using zoledronic acid (4 mg/intravenous) every 3 months to stabilize the bone lesions. CA is a heterogeneous disease with unpredictable progression and uncertain treatment. So, it is highly recommended to disseminate research findings of all such rare cases to find any new pathophysiological findings and establish an effective treatment.

## Linked entities

- **Chemicals:** zoledronic acid (PubChem CID 68740)

## Full-text entities

- **Diseases:** bone lesions (MESH:D001847), cysts (MESH:D003560), lytic lesions (MESH:D009059), dyspnea (MESH:D004417), CA (MESH:D010015), pain (MESH:D010146), lower back ache (MESH:D017116)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12055252/full.md

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12055252/full.md

## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12055252/full.md

---
Source: https://tomesphere.com/paper/PMC12055252