# Downward hyperinflation of the native lung after right single lung transplantation for COPD: A case report highlighting diaphragmatic mobility

**Authors:** Shin Tanaka, Tsuyoshi Ryuko, Yasuaki Tomioka, Kazuhiko Shien, Ken Suzawa, Kentaroh Miyoshi, Mikio Okazaki, Seiichiro Sugimoto, Shinichi Toyooka

PMC · DOI: 10.1016/j.jhlto.2025.100268 · 2025-04-08

## TL;DR

A patient with COPD who received a right lung transplant showed improved function due to the native left lung's hyperinflation and diaphragm movement.

## Contribution

The study highlights diaphragmatic mobility's role in preventing compression of the transplanted lung in right single lung transplants.

## Key findings

- Hyperinflation of the native left lung occurred without compressing the transplanted lung.
- Diaphragm mobility, aided by the absence of the liver, contributed to favorable outcomes.
- Right single lung transplantation can maintain function despite native lung expansion.

## Abstract

A 60-year-old male with COPD underwent right single lung transplantation. Despite progressive hyperinflation of the native left lung, the transplanted lung maintained function, as downward expansion of the left lung displaced the diaphragm without compressing the mediastinum. This suggests diaphragm mobility, aided by the absence of the liver beneath the left diaphragm, contributes to favorable outcomes in right single lung transplantation by preventing mechanical compression of the transplanted lung.

## Linked entities

- **Diseases:** COPD (MONDO:0005002)

## Full-text entities

- **Diseases:** COPD (MESH:D029424)

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12053984/full.md

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Source: https://tomesphere.com/paper/PMC12053984