Ustekinumab is effective in the treatment of linear psoriasis: a case report and literature review
Jinxu Qi, Qing Zhu, Mengdi Feng, Lijuan Liu, Guoqiang Zhang
TL;DR
This paper reports a successful case of treating linear psoriasis with ustekinumab and reviews existing literature to guide clinicians.
Contribution
The novelty lies in reporting the first known case of ustekinumab's efficacy in treating linear psoriasis.
Findings
Ustekinumab effectively treated a case of linear psoriasis.
Linear psoriasis is rare and less responsive to standard treatments.
Genetic mosaicism may contribute to the pathogenesis of linear psoriasis.
Abstract
Linear psoriasis is a rare type of psoriasis that usually presents as scaly papules and plaques unilaterally distributed along the Blaschko line. Currently, the pathogenesis of linear psoriasis is not fully understood, and genetic mosaicism may be one of the explanations. As linear psoriasis is less responsive to treatment than psoriasis vulgaris, there is no consensus on treatment guidelines specifically for this disease, and the efficacy of ustekinumab in treating this category has not been reported. In this article, we present a case of effective treatment of linear psoriasis with ustekinumab and review the relevant literature, hoping to help clinicians better understand and treat this disease.
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Taxonomy
TopicsPsoriasis: Treatment and Pathogenesis · Autoimmune Bullous Skin Diseases · Skin and Cellular Biology Research