# Diffuse Multifocal Intracranial Hemorrhage Following Alteplase Infusion: A Case Image Report

**Authors:** Abdallah Alwali, Mohanad Faisal, Naveed Akhtar

PMC · DOI: 10.1002/ccr3.70263 · 2025-05-05

## TL;DR

This case report highlights a rare but serious brain hemorrhage complication after a clot-busting treatment for stroke.

## Contribution

The report emphasizes the need for vigilance in monitoring atypical bleeding and blood pressure control post-treatment.

## Key findings

- Diffuse multifocal intracranial hemorrhage occurred after alteplase infusion.
- Timely recognition and blood pressure control are critical for better outcomes.
- Atypical bleeding sites require careful monitoring in post-thrombolysis stroke patients.

## Abstract

Hemorrhage beyond the ischemic area is an uncommon but serious complication of thrombolysis. This case underscores the importance of timely recognition of atypical bleeding sites, careful monitoring, and strict blood pressure control to improve outcomes in ischemic stroke patients post‐thrombolysis.

## Linked entities

- **Diseases:** ischemic stroke (MONDO:1060198)

## Full-text entities

- **Diseases:** ischemic (MESH:D002545), Hemorrhage (MESH:D006470), Alteplase Infusion (MESH:D000075662), ischemic stroke (MESH:D002544), Intracranial Hemorrhage (MESH:D020300)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12053039/full.md

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Source: https://tomesphere.com/paper/PMC12053039