# Histological study of donor/recipient feasibility in distal nerve transfer for the upper limb nerve injury

## TL;DR

This study examines the feasibility of using donor nerves to restore function in injured upper limb nerves by analyzing axon compatibility in cadaveric specimens.

## Contribution

The study introduces a histological evaluation of donor/recipient nerve compatibility in distal nerve transfers for radial and ulnar nerve palsy.

## Key findings

- Median-radial nerve transfers showed sufficient donor axons, while median-ulnar transfers had a shortage.
- Combining different nerve transfers may improve motor recovery by compensating for donor axon shortages.

## Abstract

This study aimed to histologically investigate whether the compatibility of donor and recipient nerves in distal nerve transfer for radial and ulnar nerve palsy is suitable for restoring nerve function. Partial median to radial nerve transfer for radial nerve palsy and partial median to ulnar nerve transfer for ulnar nerve palsy were performed in 10 cadaveric upper limbs fixed using the Thiel technique. Histological analysis of the nerve samples at the coaptation site focused on the number of myelinated axons. Each recipient and donor nerve was identified in all specimens without any anatomical variations. While median-radial nerve transfer techniques showed an adequate number of donor axons, median-ulnar nerve transfer techniques showed a shortage of donor axons. The insufficiency of donor axons compared to the recipient axons may explain the challenges in reinnervating the recipient muscles. Combining the two different nerve transfers may compensate for the shortage of donor axons and improve motor recovery. Type of study and Level of evidence: Therapeutic, Level III.