# Chronic cough due to laryngeal hamartoma: A case report

## TL;DR

A rare case of chronic cough caused by a laryngeal hamartoma in a patient with Bardet-Biedl syndrome is reported, highlighting the importance of histopathology and surgical management.

## Contribution

This is the first reported case of laryngeal hamartoma in a patient with Bardet-Biedl syndrome.

## Key findings

- Histopathology distinguished post-surgical recurrence from an inflammatory reaction.
- Successful treatment involved excision, cautery, and follow-up with laryngoscopy and imaging.

## Abstract

Laryngeal hamartomas (LHs) are rare, benign tumor-like growths arising from disorganized mature tissues. Bardet-Biedl syndrome (BBS) is a ciliopathy with multisystem manifestations. This article presents a rare case of LH presented with chronic cough.

A male in his 30s with BBS presented with a six-month history of persistent productive cough unresponsive to standard treatments. Video rhinolaryngoscopy and CT imaging identified a polyp on the anterior wall of the epiglottis. Histopathology confirmed the diagnosis of a hamartoma. Initial surgical excision was performed, preceded by a single IV dose of Hydrocortisone. Systemic corticosteroid therapy with oral Prednisolone tablets were prescribed postoperatively. Despite initial symptom resolution, the lesion recurred, necessitating re-excision and cautery. Histopathology suggested an inflammatory reaction rather than true recurrence.

LHs are uncommon, with fewer than 35 cases documented. They often mimic other laryngeal lesions, making diagnosis reliant on histopathological evaluation. This case marks the first reported instance of LH in a BBS patient. Management approaches, including careful surgical excision and post-operative care, are crucial to preserving laryngeal function.

LH is a rare but important consideration in cases of chronic cough, especially when common causes have been ruled out.

•Rare case of chronic cough caused by laryngeal hamartoma (LH)•Histopathological findings differentiated recurrence from inflammatory reaction post-surgery.•Successful management involved excision, monopolar cautery, and tailored follow-up care with laryngoscopy and imaging.

Rare case of chronic cough caused by laryngeal hamartoma (LH)

Histopathological findings differentiated recurrence from inflammatory reaction post-surgery.

Successful management involved excision, monopolar cautery, and tailored follow-up care with laryngoscopy and imaging.