RETRACTION: NGF Protects Neuroblastoma Cells Against β‐Amyloid‐Induced Apoptosis via the Nrf2/HO‐1 pathway

TL;DR

This retracted study claimed that NGF protects neuroblastoma cells from β-amyloid-induced cell death through a specific pathway, but the findings are no longer considered reliable due to image duplication issues.

Contribution

The paper originally proposed a novel protective mechanism involving NGF and the Nrf2/HO-1 pathway in neuroblastoma cells.

Findings

NGF was reported to protect neuroblastoma cells from β-amyloid-induced apoptosis.

The protective effect was suggested to involve the Nrf2/HO-1 signaling pathway.

The study was retracted due to image duplication and compromised data integrity.

Abstract

RETRACTION: R. Su, W. Su, and Q. Jiao, “NGF Protects Neuroblastoma Cells Against β‐Amyloid‐Induced Apoptosis via the Nrf2/HO‐1 pathway,” FEBS Open Bio 9, no. 12 (2019): 2063‐2071, https://doi.org/10.1002/2211‐5463.12742.

The above article, published online on 01 November 2019, in Wiley Online Library (wileyonlinelibrary.com), and its correction (https://doi.org/10.1002/2211‐5463.12782) has been retracted by agreement between the journal Editor‐in‐Chief, Miguel A. De la Rosa; FEBS Press; and John Wiley and Sons Ltd. The retraction has been agreed upon following an investigation into concerns raised by a third party, which revealed inappropriate image duplications between this (Figure 2A, 3A, 5A and 6E) and other articles that were previously published or published in the same or following year. Given the extent of the identified issues, the editors have lost confidence in the data presented and consider the conclusions of this manuscript substantially compromised.