# Cystic Change in Pleomorphic Adenoma: A Rare Entity

**Authors:** Vattikuti Satya Veni, Atla Bhagyalakshmi, Sri Keerthika, Roohi Firdous

PMC · DOI: 10.7759/cureus.81683 · 2025-04-04

## TL;DR

This paper presents a rare case of a cystic change in a pleomorphic adenoma, a type of tumor that can be difficult to diagnose correctly.

## Contribution

The novelty lies in reporting a unique case of cystic pleomorphic adenoma that poses diagnostic challenges.

## Key findings

- Cystic changes in pleomorphic adenomas can mimic other malignancies, complicating diagnosis.
- A 41-year-old man presented with a rare case of cystic pleomorphic adenoma.

## Abstract

Pleomorphic adenomas most frequently affect the parotid gland, primarily the superficial lobe. The cystic change, which can resemble squamous cell carcinoma, mucoepidermoid carcinoma, mucocele, or carcinoma ex pleomorphic adenoma, presents a diagnostic challenge in pleomorphic adenomas. Here, we report a unique and intriguing case of cystic pleomorphic adenoma in a 41-year-old man.

## Linked entities

- **Diseases:** pleomorphic adenoma (MONDO:0008401), squamous cell carcinoma (MONDO:0005096), mucoepidermoid carcinoma (MONDO:0003036), carcinoma ex pleomorphic adenoma (MONDO:0002472)

## Full-text entities

- **Diseases:** mucoepidermoid carcinoma (MESH:D018277), Pleomorphic Adenoma (MESH:D008949), squamous cell carcinoma (MESH:D002294), mucocele (MESH:D009078), carcinoma (MESH:D009369)

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12049666/full.md

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Source: https://tomesphere.com/paper/PMC12049666