# Recalcitrant Fovea-Involving Macular Fold After Uneventful Epiretinal Membrane Surgery

**Authors:** Matteo Mario Carlà, Carlos Mateo

PMC · DOI: 10.22336/rjo.2025.20 · 2025-01-01

## TL;DR

A young man developed a persistent macular fold after a routine eye surgery, leading to lasting vision issues.

## Contribution

This case report highlights a rare complication of macular folds after ERM surgery and suggests early surgical intervention may be necessary.

## Key findings

- A fovea-involving macular fold developed after ERM surgery, causing intractable metamorphopsia.
- Surgical interventions failed to resolve the macular fold over a year after initial surgery.
- Incorrect patient positioning may have contributed to the vertical orientation of the macular fold.

## Abstract

To describe a case of recalcitrant fovea-involving macular folds developing after uncomplicated epiretinal membrane (ERM) peeling and causing intractable metamorphopsia.

Case report.

A 22-year-old man with a stage 3 ERM, visual acuity (VA) of 20/100, and a history of scleral buckle underwent pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling. One week after surgery, VA dropped to 20/125 with worsened metamorphopsia. Ophthalmoscopy revealed a fovea-involving full-thickness macular fold, with photoreceptor outer segments in opposition. After 3 weeks of follow-up without improvement, PPV with induction of localized retinal detachment was performed, combined with retinal massage. Moreover, perfluorocarbon liquid (PFCL) was employed to stretch the retina. Nevertheless, the macular fold and metamorphopsia were unchanged, even one year after the first surgery.

We hypothesize that, due to the highly contracted ERM, the retina may have separated from the RPE during peeling and folded over in the first postoperative days. Concurrently, incorrect patient positioning under air tamponade might have contributed to the vertical orientation of the fold.

Even if macular folds after ERM surgery are rare, prompt surgical treatment rather than watchful waiting should be considered to prevent permanent functional impairment.

## Full-text entities

- **Diseases:** metamorphopsia (MESH:D014786), ERM (MESH:D019773), Fovea (MESH:C538369), air (MESH:D004618), retinal detachment (MESH:D012163), macular folds (MESH:D057165)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12049659/full.md

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Source: https://tomesphere.com/paper/PMC12049659