# Primary peritonitis: an enigmatic case and literature exploration-diagnostic challenges and therapeutic approaches (case report)

**Authors:** Amina Chaka, Wael Boujelbène, Amin Chaabouni, Amin Zouari, Mahmoud Kammoun, Ines Ben Hammouda, Housem Harbi, Salah Boujelbène

PMC · DOI: 10.11604/pamj.2025.50.23.43398 · The Pan African Medical Journal · 2025-01-13

## TL;DR

A 24-year-old patient with no medical history presented with peritonitis of unknown origin, diagnosed via laparoscopy and treated with antibiotics.

## Contribution

This case report highlights diagnostic and therapeutic challenges in managing primary peritonitis with no clear source.

## Key findings

- Laparoscopic exploration confirmed peritonitis but found no obvious cause.
- Bacteriological tests of peritoneal fluid and blood cultures were negative.
- The patient recovered uneventfully after peritoneal cleansing and antibiotic therapy.

## Abstract

Primary peritonitis, also known as spontaneous peritonitis, is rare and has no obvious intra-abdominal origin. Antibiotic therapy is usually sufficient. However, surgery is sometimes necessary when the primary character of the peritonitis is uncertain. We report herein the case of a 24-year-old patient, with no particular medical history and who presented to the emergency department for diffuse abdominal pain with fever. Abdominal examination found diffuse abdominal tenderness with hyperleukocytosis. A computed tomography scan showed generalized intraperitoneal effusion with no obvious abdominal infectious hotbed, nor pneumoperitoneum. However, it showed lateral basal pneumonia. Laparoscopic exploration confirmed the diagnosis of peritonitis but didn´t find any obvious cause. She had a peritoneal cleansing with an appendectomy of principle. Then she was put on probabilistic broad-spectrum parenteral antibiotic therapy. However bacteriological examination of the peritoneal fluid and blood cultures were negative. The surgical postoperative course was uneventful and she was discharged at post-operative day 5.

## Linked entities

- **Diseases:** peritonitis (MONDO:1010128), pneumonia (MONDO:0005249)

## Full-text entities

- **Diseases:** intraperitoneal effusion (MESH:D000080324), abdominal tenderness (MESH:D000007), pneumoperitoneum (MESH:D011027), fever (MESH:D005334), abdominal pain (MESH:D015746), Primary peritonitis (MESH:D010538), basal pneumonia (MESH:D011014)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12049144/full.md

## References

10 references — full list in the complete paper: https://tomesphere.com/paper/PMC12049144/full.md

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Source: https://tomesphere.com/paper/PMC12049144