# Psychiatric Presentation of Wilson’s Disease: A Rare Disease With an Unusual Manifestation

**Authors:** Inês Baptista, Patrick Alves

PMC · DOI: 10.7759/cureus.81645 · Cureus · 2025-04-03

## TL;DR

This paper discusses a rare disease, Wilson’s disease, where psychiatric symptoms like suicidal thoughts and sleep issues were the main signs.

## Contribution

The novelty lies in highlighting unusual psychiatric manifestations and therapy nonadherence in chronic illness through a case study.

## Key findings

- Suicidal ideation and severe sleep disturbance were central symptoms in a Wilson’s disease case.
- Psychiatric symptoms in uncompensated Wilson’s disease can mimic other mental health issues.
- Therapy nonadherence in chronic illness is influenced by psychological factors.

## Abstract

Wilson’s disease is a rare disorder characterized by the accumulation of copper in multiple organs. Psychiatric symptoms are somewhat common but can take many different forms, which complicates their identification. We present a case where suicidal ideation and severe sleep disturbance were the central symptoms of the initial presentation. This case shows how psychiatric symptoms in uncompensated Wilson’s disease can look like and how they are managed, as well as a psychological perspective into therapy nonadherence in chronic illness.

## Linked entities

- **Diseases:** Wilson’s disease (MONDO:0010200)

## Full-text entities

- **Diseases:** Wilson's Disease (MESH:D006527), suicidal ideation (MESH:D001072), chronic illness (MESH:D002908), Psychiatric (MESH:D001523), sleep disturbance (MESH:D012893)
- **Chemicals:** copper (MESH:D003300)

## Full text

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## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12048889/full.md

## References

14 references — full list in the complete paper: https://tomesphere.com/paper/PMC12048889/full.md

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Source: https://tomesphere.com/paper/PMC12048889