# Multiple Ulcers Associated With Deep Vein Thrombosis Secondary to Herpes Zoster Infection of the Lower Limb

**Authors:** Makoto Kondo, Koji Habe, Keiichi Yamanaka

PMC · DOI: 10.1002/ccr3.70264 · 2025-05-01

## TL;DR

This paper discusses how herpes zoster in the lower limb can lead to deep vein thrombosis and ulcers, emphasizing early diagnosis and pain management.

## Contribution

The paper highlights the novel association between herpes zoster infection and deep vein thrombosis, emphasizing the role of pain management in prevention.

## Key findings

- Persistent limb swelling and ulceration after herpes zoster may indicate deep vein thrombosis.
- Pain and reduced mobility contribute to thrombosis, stressing the need for effective pain management.

## Abstract

Persistent limb swelling and ulceration following herpes zoster may indicate the development of deep vein thrombosis, highlighting the importance of early diagnosis and initiation of anticoagulant therapy. Pain and reduced mobility are significant contributors to thrombosis, underscoring effective pain management's critical role in the prevention of deep vein thrombosis.

## Linked entities

- **Diseases:** herpes zoster (MONDO:0005609)

## Full-text entities

- **Diseases:** Pain (MESH:D010146), thrombosis (MESH:D013927), Ulcers (MESH:D014456), swelling (MESH:D004487), Limb (MESH:D001259), Herpes Zoster Infection of (MESH:D006562), Deep Vein Thrombosis (MESH:D020246)

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12045787/full.md

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Source: https://tomesphere.com/paper/PMC12045787