# High Prevalence of Influenza D Virus Infection in Swine, Northern Ireland

## TL;DR

Influenza D virus was found in many swine herds in Northern Ireland, with new mutations identified in key viral proteins.

## Contribution

The study reports the high prevalence of influenza D virus in swine and identifies novel mutations in viral proteins.

## Key findings

- Influenza D virus was detected in multiple swine herds in Northern Ireland.
- Whole-genome sequencing revealed several circulating genotypes and novel mutations in viral proteins.

## Abstract

We detected influenza D virus in multiple swine herds in Northern Ireland. Whole-genome sequencing showed several circulating genotypes and novel mutations in the receptor-binding site and esterase domains of the hemagglutinin-esterase fusion protein. Transmission routes of influenza D virus to swine remain to be clarified but could be direct or indirect.