# Normative data for dimensions of the frontal and infraorbital nerves

**Authors:** Jessica Y. Tong, Jeffrey Sung, Khizar Rana, WengOnn Chan, Alkis J. Psaltis, Dinesh Selva

PMC · DOI: 10.1038/s41433-025-03679-4 · 2025-02-07

## TL;DR

This study provides standard measurements for the width of the frontal and infraorbital nerves to help identify abnormal enlargements linked to diseases.

## Contribution

The paper introduces normative width measurements for the frontal and infraorbital nerves using cadaveric dissection.

## Key findings

- The mean width of the frontal nerve was 2.27 ± 0.66 mm.
- The infraorbital nerve had a mean width of 3.31 ± 0.68 mm.
- The upper limit of normal for nerve widths was defined as 2 SD above the mean.

## Abstract

To present a series of normative measurements for the width of the frontal and infraorbital nerve branches of V1 and V2, respectively.

Cadaveric dissection study of 15 embalmed cadaver heads (30 orbits). The frontal nerve was excised en bloc from the superior orbital rim to the superior orbital fissure. Similarly, the infraorbital nerve was excised en bloc from the inferior orbital rim to the orbital apex. Measurements were recorded of the maximal width of the frontal nerve, infraorbital nerve within the orbital floor, and pterygopalatine segment of the maxillary nerve. Any value greater than 2 standard deviations (SD) above the mean value, was defined as nerve enlargement.

The mean transverse diameter of the frontal nerve was 2.27 ± 0.66 mm (1 SD). The mean transverse diameter of the infraorbital nerve branch, and the maxillary nerve within the pterygopalatine fossa, was 3.31 ± 0.68 mm (1 SD) and 3.59 ± 0.76 mm (1 SD), respectively. The upper limit of normal, defined as 2 SD above the mean value, for the widths of the frontal nerve, infraorbital nerve, and pterygopalatine segment of V2 widths were 3.59 mm, 4.67 mm, and 5.10 mm, respectively.

The frontal and infraorbital nerves are implicated in various inflammatory and neoplastic orbital pathologies. Defining the normative data for width is important to compare with pathological states.

## Full-text entities

- **Diseases:** nerve enlargement (MESH:D006332), inflammatory (MESH:D007249)

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Source: https://tomesphere.com/paper/PMC12043923