# The cost of rehabilitation after critical illness: a comparison of hospitalization costs for traumatic brain injury and non-traumatic brain injury patients with disorders of consciousness

**Authors:** Miao Yu, Zhongmou Huang, Yansui Yang, Yulin Wang, Hai Ren, Shilan Tang

PMC · DOI: 10.3389/fpubh.2025.1552162 · 2025-04-17

## TL;DR

This study compares hospitalization costs for traumatic and non-traumatic brain injury patients with disorders of consciousness, identifying factors that influence rehabilitation expenses.

## Contribution

The study provides insights into cost determinants for rehabilitation in critical illness recovery, focusing on traumatic versus non-traumatic brain injury patients.

## Key findings

- TBI and non-TBI patients had similar median hospitalization costs, but TBI patients had longer stays.
- Rehabilitation, medication, and treatment were the highest cost components for both groups.
- Non-TBI etiology, local residency, and traditional Chinese medicine were associated with higher costs.

## Abstract

This study aims to compare hospitalization costs between traumatic brain injury (TBI) and non-traumatic brain injury (non-TBI) patients with disorders of consciousness (DoC) to explore cost determinants.

A retrospective analysis was conducted on 210 DoC inpatients admitted to Shenzhen Longcheng Hospital, a tertiary rehabilitation hospital located in China’s Pearl River Delta region, between 2015 and 2020. Patients were categorized into TBI (n = 44) and non-TBI (n = 166) groups based on etiology. Demographic, clinical, and hospitalization cost data were collected for each patient. The study compared the cost composition for DoC patients by etiology and used multivariate analysis to identify factors influencing hospitalization costs.

The median length of stay (LOS) and cost for TBI patients were 363.5 days and $57,366.05, respectively, while for non-TBI patients, the medians were 280.5 days and $57,117.64. Across both groups, the highest cost components were rehabilitation, medication, and treatment expenses. Factors associated with higher hospitalization costs included non-TBI etiology, local residents, medical insurance, LOS, self-employed, surgical treatment, and traditional Chinese medicine (TCM) intervention.

Hospitalization cost structures were similar across etiologies, emphasizing value-driven care priorities. Key factors associated with higher hospitalization costs included non-TBI etiology, local residency, medical insurance, LOS, self-employment status, surgery, and TCM. These findings highlight key drivers of healthcare costs in DoC care, emphasizing the need for targeted policy interventions. However, given the limitations of this study, further research with larger, more diverse samples is essential to comprehensively assess the impact of costs on patient outcomes and care quality.

## Linked entities

- **Diseases:** traumatic brain injury (MONDO:0858950)

## Full-text entities

- **Diseases:** DoC (MESH:D003244), TBI (MESH:D000070642), critical illness (MESH:D016638)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12043689/full.md

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Source: https://tomesphere.com/paper/PMC12043689