# Extracardiac Compression by Gastrointestinal Structures: A Comprehensive Anthology From the Literature

## TL;DR

This paper reviews how gastrointestinal structures can compress the heart, highlighting the need for better recognition and diagnosis in clinical practice.

## Contribution

The paper provides a comprehensive literature review on extracardiac heart compression by GI structures, which is often overlooked.

## Key findings

- Extracardiac heart compression by GI structures is underrecognized but clinically significant.
- A variety of GI etiologies and cardiac chamber involvement scenarios exist.
- Comprehensive imaging is essential for timely diagnosis and avoiding misinterpretations.

## Abstract

Extrinsic heart compression by gastrointestinal (GI) structures is an often underrecognized finding in clinical practice. It is potentially related to unpredictable clinical conditions, ranging from incidental detection in asymptomatic subjects, to deranging and potentially life-threatening clinical manifestations. However, despite its potential clinical relevance, there is still no comprehensive analysis investigating the surrounding causes, clinical findings, and diagnostic imaging work-up for this patient population. A narrative review with an extensive bibliographic search of the literature was performed using PubMed (MEDLINE), Embase, and Cochrane Central Databases up to December 31, 2023. Despite the broad spectrum of GI etiologies, clinical manifestations, and cardiac chamber involvement scenarios, physicians must be aware of such an uncommon condition, in order to provide timely diagnosis through a comprehensive imaging approach, avoid misleading interpretations, and determine the most appropriate decision-making strategy.