# Editorial: Mechanistic and statistical modeling approaches to study alloimmune T-cell responses

**Authors:** Mario Castro, Josep Bassaganya-Riera, Miguel Fribourg

PMC · DOI: 10.3389/fimmu.2025.1591083 · Frontiers in Immunology · 2025-04-16

## Full-text entities

- **Genes:** TRBV20OR9-2 (T cell receptor beta variable 20/OR9-2 (non-functional)) [NCBI Gene 6962] {aka CDR3, TCRBV20S2, TCRBV2O, TCRBV2S2O}, CD8A (CD8 subunit alpha) [NCBI Gene 925] {aka CD8, CD8alpha, IMD116, Leu2, p32}, Ppbp (pro-platelet basic protein) [NCBI Gene 246358] {aka Cxcl7, Nap-2}, PTPRC (protein tyrosine phosphatase receptor type C) [NCBI Gene 5788] {aka B220, CD45, CD45R, GP180, IMD105, L-CA}, Thbs1 (thrombospondin 1) [NCBI Gene 445442] {aka TSP-1, Tsp1}, F13a1 (coagulation factor XIII A1 chain) [NCBI Gene 60327] {aka F13a}, HLA-A (major histocompatibility complex, class I, A) [NCBI Gene 3105] {aka HLAA}, Vcl (vinculin) [NCBI Gene 305679], Ccr7 (C-C motif chemokine receptor 7) [NCBI Gene 12775] {aka CC-CKR-7, CCR-7, CD197, Cdw197, Cmkbr7, EBI1}, Src (SRC proto-oncogene, non-receptor tyrosine kinase) [NCBI Gene 83805]
- **Diseases:** cerebral infarction (MESH:D002544), ischemia (MESH:D007511), TCRs (MESH:D016399), COVID-19 (MESH:D000086382)
- **Chemicals:** ciprofibrate (MESH:C019304), alpha-linolenic acid (MESH:D017962)
- **Species:** Homo sapiens (human, species) [taxon 9606], Burkholderia pseudomallei (species) [taxon 28450], Rattus norvegicus (brown rat, species) [taxon 10116], Severe acute respiratory syndrome coronavirus 2 (no rank) [taxon 2697049], Mus musculus (house mouse, species) [taxon 10090], Ebola virus [taxon 186536]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12040956/full.md

---
Source: https://tomesphere.com/paper/PMC12040956