# Acute changes in urinary metabolites: vinyasa yoga compared to cycle ergometer exercise

**Authors:** Colin E. S. Campbell, Carl J. Murphy, Zeinab Barati, Robert H. Coker

PMC · DOI: 10.3389/fspor.2025.1556989 · Frontiers in Sports and Active Living · 2025-04-16

## TL;DR

This study compares how vinyasa yoga and cycling affect urine metabolites, finding that cycling causes more significant changes.

## Contribution

The study provides new insights into the metabolic responses of vinyasa yoga versus moderate aerobic exercise.

## Key findings

- Cycling caused greater changes in urinary metabolites like creatinine and phenylalanine compared to yoga.
- No significant difference in lactate changes was observed between the two exercises.
- The metabolic demand of yoga appears to be more distributed compared to cycling.

## Abstract

Increased interest in unconventional exercise such as vinyasa yoga has outpaced our understanding of the physiological response to yoga exercise. The objective of the current study was to evaluate changes in urinary metabolites (i.e., alanine, phenylalanine, glycine, choline, taurine, creatinine, creatine, dimethylamine, citrate, pyruvate, acetate, and beta-hydroxybutyrate) elicited by vinyasa yoga compared to moderate intensity aerobic exercise in young healthy adults.

Twelve participants, six women and six men, completed a vinyasa yoga exercise session (VY) and a moderate intensity cycle ergometer exercise session (ME) in a sequential fashion. The intensity of the ME was matched to heart rate and rating of perceived exertion elicited during the initial VY. Urine samples were collected at baseline and following the completion of each of VY and ME. Metabolite concentrations after each exercise were normalized to their baseline levels to obtain a relative exercise-induced change in concentration. We hypothesized that activation of large muscle groups in the lower extremities would foster greater ME-induced alterations in metabolites.

Exercise-induced changes in urinary concentrations of phenylalanine, creatinine, creatine, glycine, choline, taurine, dimethylamine, citrate, pyruvate, alanine, and beta-hydroxybutyrate were greater in ME compared to VY (P < 0.05). There was no difference between the exercise-induced changes in lactate between groups (P < 0.05).

The results of this study demonstrate that ME promotes more robust changes in urinary metabolites compared to VY. These differences may be due to a greater localized workload on the large muscle groups of the lower extremities during ME, and potentially highlight the distributed metabolic demand of VY.

## Linked entities

- **Chemicals:** alanine (PubChem CID 239), phenylalanine (PubChem CID 994), glycine (PubChem CID 750), choline (PubChem CID 305), taurine (PubChem CID 1123), creatinine (PubChem CID 588), creatine (PubChem CID 586), dimethylamine (PubChem CID 674), citrate (PubChem CID 31348), pyruvate (PubChem CID 107735), acetate (PubChem CID 175), beta-hydroxybutyrate (PubChem CID 441), lactate (PubChem CID 61503)

## Full-text entities

- **Chemicals:** taurine (MESH:D013654), pyruvate (MESH:D019289), phenylalanine (MESH:D010649), choline (MESH:D002794), dimethylamine (MESH:C034516), acetate (MESH:D000085), beta-hydroxybutyrate (MESH:D020155), creatinine (MESH:D003404), glycine (MESH:D005998), lactate (MESH:D019344), citrate (MESH:D019343), alanine (MESH:D000409), creatine (MESH:D003401)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

20 references — full list in the complete paper: https://tomesphere.com/paper/PMC12040866/full.md

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Source: https://tomesphere.com/paper/PMC12040866