# Perioperative Hemostasis Management During Open Mitral Valve Replacement in a Patient With Hypoprothrombinemia Secondary to Lupus Anticoagulant

## TL;DR

This case report describes the successful management of a rare coagulation disorder during heart surgery in a patient with lupus anticoagulant.

## Contribution

The paper presents the first documented case of mitral valve surgery in a patient with hypoprothrombinemia due to lupus anticoagulant.

## Key findings

- A 47-year-old patient with lupus anticoagulant and hypoprothrombinemia underwent successful mitral valve replacement.
- Multidisciplinary hemostasis management was critical for safe surgical outcomes in this rare condition.
- The case highlights the importance of tailored coagulation strategies in complex cardiac surgeries.

## Abstract

Hypoprothrombinemia is a rare coagulopathy that complicates surgical interventions and is an uncommon manifestation of lupus anticoagulant. Perioperative coagulopathy is a major challenge in cardiac surgery. To our knowledge, the management of cardiac surgery in patients with hypoprothrombinemia has not been described in prior literature. This case report outlines the challenging surgical intervention of mitral valve replacement in a 47-year-old female patient with rheumatic valve disease (RHD) and a rare prothrombin deficiency secondary to lupus anticoagulant. This report details the multidisciplinary perioperative hemostasis management and outcomes.