# Co-designing a web-based intervention (RESTORE) to support self-management of cancer-related fatigue in people living with a brain tumour

## TL;DR

Researchers co-designed a web-based tool called RESTORE to help people with brain tumors manage cancer-related fatigue, focusing on making it adaptable to their unique needs.

## Contribution

The study introduces a co-designed, web-based intervention tailored for self-management of cancer-related fatigue in people with brain tumors.

## Key findings

- Forty participants identified four themes for improving RESTORE, emphasizing the need for flexible and tailored content.
- Thirty-two modifications were suggested to optimize RESTORE for brain tumor patients, including addressing digital access and literacy barriers.
- A brain tumor-specific version of RESTORE was found to be acceptable for addressing fatigue in this population.

## Abstract

Cancer-related fatigue (CRF) is a debilitating symptom commonly reported by people with a brain tumour (BT). Many interventions have been developed to reduce CRF; however, few have been evaluated in people with BT despite the unique functional deficits experienced by this population. We aimed to explore the appropriateness of a web-based intervention (RESTORE) to support self-management of fatigue for people with a BT and identify recommended modifications.

Semi-structured interviews were conducted with people with BT, their caregivers and healthcare professionals (HCPs) who treat them. Interviews explored the appropriateness of RESTORE for this population, and suggested modifications to improve relevance and suitability. Interviews were transcribed and analysed thematically using interpretive description to devise recommendations.

Forty participants were interviewed (24 people with BT, 5 caregivers, 11 HCPs). Four themes were identified: feedback on content; feedback on format; feedback on use; and, barriers to engagement. These themes were linked by an overarching need for flexible and responsive tailoring to the unique needs of people with BT. Thirty-two recommended modifications were derived from feedback to optimise RESTORE for this population.

Results suggest a BT-specific version of RESTORE would be acceptable to address fatigue in this population. Recommended adaptations include greater flexibility and tailoring of content and format for effective use among people with BT. Barriers to engagement including digital access and literacy and awareness of the resource should be addressed in the implementation of a BT-specific version of RESTORE.

The online version contains supplementary material available at 10.1007/s00520-025-09471-0.