# Front Cover

## TL;DR

This paper explores how exosomes play a dual role in Parkinson’s disease and how adenine can help.

## Contribution

The study reveals adenine's beneficial effect in Parkinson’s disease through exosome mechanisms.

## Key findings

- Exosomes contribute to both progression and protection in Parkinson’s disease.
- Adenine shows a protective effect by modulating exosome activity.
- The dual role of exosomes is influenced by adenine treatment.

## Abstract

The cover image is based on the article Dual Role of Exosomes in Parkinson’s Disease: Adenine Exerts a Beneficial Effect by Lei Chen et al., https://doi.org/10.1111/cns.70331.