# Radiation-Induced Fibrosarcoma in the Stoma: A Case Report and Literature Review

**Authors:** Zhao Li, Liang Fang, Liang Lv, Xinjia He, Wenqiang Luo, Dong Guo, Zhen Liu

PMC · DOI: 10.1155/cris/5313214 · Case Reports in Surgery · 2025-04-21

## TL;DR

A case of fibrosarcoma developing at a stoma site after radiation therapy is reported, highlighting the rare but possible link between radiation and this type of cancer.

## Contribution

This case report adds to the limited literature on radiation-induced fibrosarcoma occurring at a stoma site following colorectal cancer treatment.

## Key findings

- A patient developed fibrosarcoma at a stoma site after receiving neoadjuvant chemoradiotherapy.
- The patient underwent stomal lumpectomy and reconstruction with no recurrence for one year.
- The patient died four years after diagnosis, indicating a poor long-term prognosis.

## Abstract

Fibrosarcoma is a rare malignant neoplasm consisting of fibroblasts with a large variety of collagen production. They usually involve deep soft tissues in extremities and trunk. However, fibrosarcoma can be seen in fields that received previous irradiation. Here, we report a case of parastomal fibrosarcoma after laparoscope-assisted extra-levator abdominal perineal resection (ELAPE) and colostomy. Prior to surgery, the patient underwent neoadjuvant chemoradiotherapy. The patient received extensive stomal lumpectomy and stoma reconstruction. The patient is free of local or distal recurrence for 1 year and died 4 years after diagnosis.

## Linked entities

- **Diseases:** fibrosarcoma (MONDO:0002676), colorectal cancer (MONDO:0005575)

## Full-text entities

- **Diseases:** Fibrosarcoma (MESH:D005354), malignant neoplasm (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12037238/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12037238/full.md

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Source: https://tomesphere.com/paper/PMC12037238