# Multi-Inflamatuar Index is a New Predictive Parameter for Early-Term Mortality in Patients Undergoing Endovascular Aortic Repair for Ruptured Abdominal Aortic Aneurysm

## TL;DR

A new inflammation-based score called MII can predict early-term mortality in patients undergoing emergency aortic repair for ruptured aneurysms.

## Contribution

The study introduces the Multi-Inflamatuar Index (MII) as a novel predictor of mortality in ruptured abdominal aortic aneurysm patients.

## Key findings

- Patients in the mortality group had significantly higher MII values compared to survivors.
- MII was identified as an independent predictor of mortality in logistic regression analysis.
- Other inflammatory markers and clinical parameters also differed significantly between groups.

## Abstract

This study aimed to investigate the predictive value of systemic inflammation markers for mortality in patients who underwent emergency endovascular aortic repair (EVAR) due to a ruptured abdominal aortic aneurysm (rAAA).

A total of 40 patients who underwent EVAR procedure due to rAAA were included in this retrospective observational cohort study. The patients were divided into 2 groups: group 1 (survivor group, n = 27) and group 2 (mortality group, n = 13). Basic clinical and demographic characteristics, hematological and biochemical parameters, and complications before the procedure were compared between the groups.

When the pre-procedural demographic and clinical characteristics of the groups were compared, the mean age in the mortality group and the survivor group was found to be 78.6 ± 6.2 and 67 ± 7.3 years, respectively. It was determined that the mean C-reactive protein value and median neutrophil-to-lymphocyte ratio, systemic immune-inflammatory index, inflammatory prognostic index, and multi-inflammatory index (MII) values in the mortality group were significantly higher than those in the survival group, and the mean lymphocyte, eosinophil, hemoglobin, platelet, plateletcrit, and albumin values were significantly lower than those in the survivor group. In the logistic regression analysis, only MII was found to be an independent predictor of mortality.

Based on the results of the current study investigating a modest number of patients, high MII levels may be used as a predictor of periprocedural mortality in patients undergoing EVAR procedure due to AAAs.