# Superior vena cava syndrome associated with sarcoidosis: a very rare case of veinous parietal involvement

**Authors:** Khaoula Boumeriem, Kaoutar Imrani, Iliass Bourekba, Nabil Moatassim Bilah, Itimad Nassar

PMC · DOI: 10.1093/omcr/omaf016 · Oxford Medical Case Reports · 2025-04-28

## TL;DR

This paper reports a rare case of superior vena cava syndrome caused by sarcoidosis, emphasizing the need to consider inflammatory thickening as a possible cause.

## Contribution

The novelty lies in highlighting granulomatous involvement as a rare cause of superior vena cava syndrome in sarcoidosis.

## Key findings

- SVCS was likely caused by granulomatous inflammation rather than compression or thrombosis.
- The case underscores the importance of considering inflammatory thickening in diagnosing SVCS.
- Appropriate treatment is necessary for such rare presentations of sarcoidosis.

## Abstract

Sarcoidosis, a systemic disorder characterized by non-caseating granulomas, poses diagnostic challenges due to its diverse manifestations. We present a rare case of superior vena cava syndrome (SVCS) secondary to most likely granulomatous involvement in a patient with mediastinal sarcoidosis. While SVCS typically arises from extrinsic compression or thrombosis, our case highlights the importance of considering inflammatory thickening of the SVC wall as a potential cause, requiring appropriate treatment.

## Linked entities

- **Diseases:** sarcoidosis (MONDO:0008399), superior vena cava syndrome (MONDO:0043287)

## Full-text entities

- **Diseases:** granulomatous (MESH:D013968), SVCS (MESH:D013479), granulomas (MESH:D006099), systemic disorder (MESH:D009422), inflammatory (MESH:D007249), Sarcoidosis (MESH:D012507), thrombosis (MESH:D013927)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12035685/full.md

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12035685/full.md

## References

7 references — full list in the complete paper: https://tomesphere.com/paper/PMC12035685/full.md

---
Source: https://tomesphere.com/paper/PMC12035685