# You are what you eat: metabolic recycling of phagocytosed bacteria modulates macrophage immunity

**Authors:** Syamantak Basu, Manuela Rossol

PMC · DOI: 10.1038/s41392-025-02222-x · Signal Transduction and Targeted Therapy · 2025-04-28

## Full-text entities

- **Genes:** Rraga (Ras-related GTP binding A) [NCBI Gene 68441] {aka 1300010C19Rik, FIP-1, RAGA}, Mtor (mechanistic target of rapamycin kinase) [NCBI Gene 56717] {aka 2610315D21Rik, FRAP, FRAP2, Frap1, RAFT1, RAPT1}, Il1b (interleukin 1 beta) [NCBI Gene 16176] {aka IL-1beta, Il-1b}
- **Diseases:** infection (MESH:D007239), infectious disease (MESH:D003141), bacterial infection (MESH:D001424), inflammation (MESH:D007249), sepsis (MESH:D018805)
- **Chemicals:** 13C (MESH:C000615229), ROS (MESH:D017382), amino acid (MESH:D000596), carbon (MESH:D002244), itaconate (MESH:C005229), GTP (MESH:D006160), nucleotides (MESH:D009711), fatty acids (MESH:D005227), AMP (MESH:D000249), 3',5'-cyclic adenosine monophosphate (-), ATP (MESH:D000255), glutathione (MESH:D005978)
- **Species:** Bacteria Latreille et al. 1825 (Bacteria stick insect, genus) [taxon 629395], Escherichia coli (E. coli, species) [taxon 562], Mus musculus (house mouse, species) [taxon 10090]

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## References

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Source: https://tomesphere.com/paper/PMC12034799