# The Hidden Cost of Bariatric Surgery: Wernicke’s Encephalopathy and Polyneuropathy

**Authors:** Lailus Sabikunnahar Mishu, Esraa Abuelgassem Hagahmed Mohamed, Tochukwu Samuel Odogwu, Muhammad Aftab Toor, NoimUddin Jibon

PMC · DOI: 10.7759/cureus.81337 · Cureus · 2025-03-28

## TL;DR

Bariatric surgery can lead to serious neurological issues due to thiamine deficiency, highlighting the need for better nutritional monitoring and patient education.

## Contribution

This case report highlights the risk of thiamine deficiency post-bariatric surgery and advocates for improved preoperative and postoperative nutritional management.

## Key findings

- A 27-year-old patient developed neurological symptoms due to thiamine deficiency after gastric sleeve surgery.
- Thiamine deficiency can lead to Wernicke’s encephalopathy and polyneuropathy, which are often overlooked post-bariatric surgery.
- The report underscores the importance of nutritional monitoring and supplementation to prevent such complications.

## Abstract

Bariatric surgery is a recognised intervention for severe obesity, a global epidemic associated with numerous comorbidities like diabetes, hypertension, and cardiovascular diseases. Procedures such as Roux-en-Y gastric bypass facilitate significant weight loss, improving metabolic health and quality of life. However, these surgeries carry hidden costs, particularly concerning nutritional deficiencies that are often overlooked in preoperative assessments.

This case report presents a 27-year-old patient who, after undergoing gastric sleeve surgery, developed neurological symptoms due to thiamine deficiency. Thiamine, essential for energy metabolism, is crucial for neurological function, and its deficiency can lead to serious conditions like Wernicke’s encephalopathy and polyneuropathy. Despite the initial success of the surgery, the patient faced significant morbidity due to this oversight.

The report emphasises the need for rigorous nutritional monitoring and proactive supplementation post-surgery. It advocates for comprehensive preoperative counselling that addresses potential deficiencies and their long-term implications. By recognising these hidden costs, healthcare providers can better prepare patients for effective long-term management, enhancing post-operative outcomes and improving the overall quality of life for those battling severe obesity.

## Linked entities

- **Chemicals:** thiamine (PubChem CID 1130)
- **Diseases:** Wernicke’s encephalopathy (MONDO:0007020), polyneuropathy (MONDO:0001824), diabetes (MONDO:0005015), obesity (MONDO:0011122)

## Full-text entities

- **Diseases:** thiamine deficiency (MESH:D013832), Wernicke's Encephalopathy (MESH:D014899), nutritional deficiencies (MESH:D044342), obesity (MESH:D009765), Polyneuropathy (MESH:D011115), neurological symptoms (MESH:D009461), weight loss (MESH:D015431), diabetes (MESH:D003920), cardiovascular diseases (MESH:D002318), hypertension (MESH:D006973)
- **Chemicals:** Thiamine (MESH:D013831)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12034089/full.md

## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12034089/full.md

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Source: https://tomesphere.com/paper/PMC12034089