# Navigating the red: Diagnostic dilemma of erythema and diffuse body rash post- intrathecal baclofen pump implantation

**Authors:** Chelsey Hoffmann, Annie Howrigon, Jennifer Hollister, William D. Mauck, Oludare O. Olatoye

PMC · DOI: 10.1016/j.inpm.2025.100584 · 2025-04-15

## TL;DR

This paper discusses the challenges in diagnosing skin reactions after intrathecal baclofen pump implantation and emphasizes the need for careful patient evaluation.

## Contribution

The paper highlights the importance of thorough patient history and multidisciplinary expertise in managing post-implant skin reactions.

## Key findings

- Skin reactions post-implant can be due to localized or systemic infections.
- Accurate diagnosis is crucial to avoid unnecessary device removal.
- Collaboration with subspecialists improves patient care outcomes.

## Abstract

Intrathecal drug delivery system (IDDS) infections can be localized to the pump pocket site and/or the catheter insertion site or become systemic, all potentially resulting in IDDS explant. Given the well-established effectiveness of IDDS for chronic non-cancer pain, cancer-associated pain, and spasticity, clinicians must differentiate between localized and systemic post-operative IDDS infections, as well as identify other causes of post-surgical skin irritation while avoiding unnecessary device explanation and therapy interruption.

In this letter-to-the-editor, we describe and discuss the importance of taking a thorough patient history and utilizing both critical clinical decision-making as well as expertise from other subspecialists to care for IDDS patients and navigate problematic skin reactions following implant.

## Full-text entities

- **Diseases:** cancer (MESH:D009369), erythema (MESH:D004890), rash (MESH:D005076), skin irritation (MESH:D012871), spasticity (MESH:D009128), infections (MESH:D007239), pain (MESH:D010146)
- **Chemicals:** baclofen (MESH:D001418)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12032324/full.md

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Source: https://tomesphere.com/paper/PMC12032324