# A radiographic analysis of humerus shaft fractures to predict non-union

**Authors:** Alexander Price, Conor O’Driscoll, Nicolaas Kotze, Danilo Vukanic, Petr Jemelik, May Cleary, David O’Briain

PMC · DOI: 10.1007/s11845-025-03905-8 · 2025-02-15

## TL;DR

This study shows that initial radiographic displacement in humerus shaft fractures can predict whether non-surgical treatment will fail.

## Contribution

The study identifies specific radiographic parameters that predict non-union in non-operatively treated humeral shaft fractures.

## Key findings

- Non-operative treatment failure was associated with increased AP translation on lateral radiographs.
- Failed conservative treatment was more common in older patients and females.
- Significant AP displacement may help guide surgical intervention decisions.

## Abstract

Humeral shaft fracture non-union rates of up to 33% have been reported when managed non-operatively. When managed surgically, non-union rates of 10% have been seen. The initial radiographic displacement parameters may be of significance in determining whether non-operative treatment might fail.

To determine whether the initial radiographic displacement of humeral shaft fractures can predict non-union rates and assist in decision-making for surgical intervention.

A retrospective cohort study was performed to identify all patients with humeral shaft fractures presenting to a regional trauma centre over a three-year period. Three-observer measurements were taken on defined radiographic parameters. These were compared between groups treated successfully with surgery and with non-operative intervention. A subset group was identified who failed non-operative treatment and required delayed surgery. Statistical analysis was performed to determine whether the group that failed non-operative treatment met the proposed radiographic parameters predicting treatment failure.

Eighty patients were identified over the defined three-year period. Failure of non-operative management occurred in 6/43 (13.95%) patients. Failed conservative treatment was associated with increased age, female gender, and increased AP translation of lateral radiographs. Fractures successfully treated non-operatively showed a significantly lower AP translation on the lateral radiographs compared to patients who failed non-operative treatment 9.69 mm (IQR 4.90–14.05 mm) versus 22.61 mm (IQR 15.73–23.83 mm), p-value = 0.042.

Significant initial AP displacement may be associated with failure of non-operative management. This study highlights the importance of initial radiographic parameters of displacement in predicting possible failure of non-operative management for midshaft humerus fractures.

## Full-text entities

- **Diseases:** trauma (MESH:D014947), Humeral shaft fracture (MESH:D006810), Fractures (MESH:D050723), AP displacement (MESH:D006617)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

8 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12031971/full.md

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Source: https://tomesphere.com/paper/PMC12031971