# Recent Developments in Automated Reactors for Plasmonic Nanoparticles

**Authors:** Shan He, Tong Luo, Xiao’e Chen, David James Young, Matt Jellicoe

PMC · DOI: 10.3390/nano15080607 · Nanomaterials · 2025-04-15

## TL;DR

This paper reviews how automated reactors are improving the synthesis of plasmonic nanoparticles through precise control and real-time monitoring.

## Contribution

The paper provides a comprehensive review of recent advancements in automated reactor systems for plasmonic nanoparticle synthesis.

## Key findings

- Automated reactors enable precise control over morphology and reaction pathways in nanomaterial synthesis.
- Emerging technologies are enhancing real-time monitoring and adaptive feedback in nanoparticle fabrication.
- Challenges remain in integrating automation for complex, multistep chemical processes.

## Abstract

Automated reactors are transforming nanomaterial synthesis by enabling precise, multistep control over morphology and reaction pathways. This review discusses recent advancements in robotic batch and continuous-flow platforms, highlighting their role in expanding chemical space exploration and adaptive manufacturing. Despite progress, challenges remain in integrating automation for complex, multistep syntheses due to the intricate interplay of chemical and physical processes. Emerging process analytical technologies and advanced control software are enhancing real-time monitoring, adaptive feedback loops, and self-optimizing synthesis strategies. We categorize these developments, emphasizing their impact on plasmonic nanomaterial fabrication and outlining future directions for autonomous synthesis.

## Full-text entities

- **Diseases:** toxicity (MESH:D064420), injury to (MESH:D014947)
- **Chemicals:** Au (MESH:D006046), silver (MESH:D012834), AgAu (-), metal (MESH:D008670), polyol (MESH:C024617), 4-nitrophenol (MESH:C024836)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12029605/full.md

## References

40 references — full list in the complete paper: https://tomesphere.com/paper/PMC12029605/full.md

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Source: https://tomesphere.com/paper/PMC12029605