# Clinical and Epidemiological Study of Leptospirosis in the Settlements of Presidente Epitacio and Mirante do Paranapanema

**Authors:** Mario A. R. Aleman, Natalia C. Gaeta, Vanessa Castro, Eduardo C. Marques, Bruno L. M. Ribeiro, Zenaide S. Olímpio, Lilian Gregory

PMC · DOI: 10.3390/microorganisms13040865 · Microorganisms · 2025-04-10

## TL;DR

This study found a high prevalence of leptospirosis in dairy cattle in two settlements in São Paulo, Brazil, highlighting the need for better control measures.

## Contribution

The study reports a high seroprevalence of Leptospira spp. in dairy cattle in rural settlements of São Paulo.

## Key findings

- The overall prevalence of Leptospira spp. was 58.93% in the studied settlements.
- A correlation was found between retained placenta and seropositivity for Leptospira spp. antibodies.
- The study emphasizes the need for public policies to address leptospirosis in the region.

## Abstract

Brazilian family farming comprises production units that represent approximately 86.40% of agricultural establishments, playing a significant national role in socio-environmental and economic sectors. The state of São Paulo is known for its rural and urban development, including agricultural settlements such as Pontal do Paranapanema. This sector requires attention due to the emergence of infectious diseases, such as leptospirosis, a widespread zoonotic disease that causes losses in agricultural productivity. This study aimed to analyze the prevalence of leptospirosis in dairy cattle within the settlements of Presidente Epitácio and Mirante do Paranapanema. All animals underwent serological testing. The overall prevalence of Leptospira spp. was 58.93%. Additionally, the prevalence of antibodies against Leptospira spp. was 59.20% in multiparous cows and 58.60% in primiparous cows. A correlation was also observed between animals with retained placenta and seropositive animals for Leptospira spp. antibodies. Based on this study, we highlight that the high prevalence of leptospirosis underscores the presence of this pathology in settlements within the Pontal do Paranapanema region. Consequently, there is a need to develop public policy programs, alongside sanitary and control measures, to mitigate the impact on dairy farming in the region.

## Linked entities

- **Diseases:** leptospirosis (MONDO:0005825)

## Full-text entities

- **Diseases:** infectious diseases (MESH:D003141), Leptospirosis (MESH:D007922), zoonotic (MESH:D015047)
- **Species:** Bos taurus (bovine, species) [taxon 9913]

## Full text

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## References

48 references — full list in the complete paper: https://tomesphere.com/paper/PMC12029453/full.md

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Source: https://tomesphere.com/paper/PMC12029453