# Endurance Training Exercise Dose in Coronary Artery Disease Rehabilitation

**Authors:** Daria Neyroud, Aaron L. Baggish

PMC · DOI: 10.3390/jcdd12040134 · 2025-04-03

## TL;DR

This paper reviews how different amounts of exercise affect heart health in patients recovering from coronary artery disease, finding that high-intensity exercise may offer the most benefits.

## Contribution

The study compares exercise doses in cardiac rehabilitation and highlights the potential benefits of high-intensity training.

## Key findings

- High-intensity exercise yields substantial improvements in cardiorespiratory fitness.
- Few studies have directly compared different exercise doses in cardiac rehabilitation.
- More research is needed to confirm the benefits of specific exercise doses.

## Abstract

Clinical management of patients with atherosclerotic coronary artery disease (CAD) following acute coronary syndrome includes cardiac rehabilitation. The well-established hallmark of cardiac rehabilitation is structured aerobic exercise training. To date, however, a limited number of studies have directly compared the effects of different doses of exercise on cardiovascular health, leaving uncertainty about the possible differential benefits of different exercise doses for use during cardiac rehabilitation. To address this area of uncertainty, we conducted a literature review and comparative analyses of studies that both compared two or more exercise interventions and assessed pre- and post-intervention peak oxygen consumption (V˙O2PEAK). Results from these analyses suggest that high exercise intensity, even when performed over relatively short duration interventions, appears to yield the most substantial improvements in cardiorespiratory fitness. However, this conclusion is based on the limited number of available studies, underscoring the need for future work examining exercise dose and clinical outcomes in the cardiac rehabilitation setting.

## Linked entities

- **Diseases:** acute coronary syndrome (MONDO:0005542)

## Full-text entities

- **Diseases:** coronary syndrome (MESH:D054058), CAD (MESH:D003324)
- **Chemicals:** oxygen (MESH:D010100)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12028330/full.md

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Source: https://tomesphere.com/paper/PMC12028330