# Vagal Nerve Biofeedback Intervention for Improving Health Outcomes Among Ukrainian Forced Migrants: A Proof-of-Concept Study

**Authors:** Yori Gidron, Einav Levy, Chen Hanna Ryder, Sharon Shaul, Rita Sirota, Drorit Atias

PMC · DOI: 10.3390/ijerph22040515 · 2025-03-28

## TL;DR

A breathing intervention targeting the vagus nerve showed promise in reducing stress and health symptoms among Ukrainian migrants.

## Contribution

A novel biofeedback-guided breathing intervention for stress reduction in forced migrant populations is proposed and tested.

## Key findings

- Significant improvements in pain perception, perceived stress, and heart rate were observed.
- The intervention was feasible and showed preliminary efficacy in a humanitarian setting.

## Abstract

Background: The ongoing conflict in Ukraine has forced numerous migrants into neighboring countries, many suffering from pre-existing or newly acquired physical and mental health conditions. Addressing these complex challenges in humanitarian settings requires innovative, evidence-based interventions that are cost-effective and easy to administer. Drawing upon research highlighting the vagus nerve’s role in regulating well-being, we hypothesized that vagal nerve activation could offer a promising therapeutic approach. Method: We conducted a proof-of-concept study in which 21 Ukrainian forced migrants were trained in a biofeedback-guided paced breathing intervention designed to stimulate the vagus nerve and promote self-regulation of stress response systems. Changes in pain perception, perceived stress, blood pressure, and heart rate were assessed before and after the vagal breathing intervention using a t-test. Correlations were examined at baseline. Results: Statistically significant improvements were observed in all measures except systolic blood pressure, providing preliminary evidence for the efficacy of vagal nerve activation in alleviating stress-related health symptoms. Conclusions: This study demonstrates the feasibility and therapeutic potential of a vagal nerve-activating intervention in a humanitarian setting. These findings warrant replication in larger, controlled trials. If substantiated, this low-cost, scalable intervention could help mitigate health burdens among forced migrant populations worldwide.

## Full-text entities

- **Diseases:** pain (MESH:D010146)

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Source: https://tomesphere.com/paper/PMC12027313