# Applications and status of gene drive in plants

**Authors:** Bruce A. Hay

PMC · DOI: 10.1371/journal.pbio.3003148 · 2025-04-15

## TL;DR

Gene drive in plants can help address issues from globalization and climate change, but plant biology makes it challenging, and self-limiting methods offer a safer approach.

## Contribution

The paper discusses the application of gene drive in plants and proposes self-limiting methods as a controlled alternative.

## Key findings

- Gene drive can be used to modify or suppress plant populations for addressing global challenges.
- Plant biology features complicate the use of gene drive.
- Self-limiting methods offer a controlled and reversible solution.

## Abstract

Gene drive can modify or suppress plant populations, offering solutions to challenges associated with globalization and climate change. However, common features of plant biology complicate its application. Self-limiting methods provide a controlled, reversible path forward.

Gene drive can modify or suppress plant populations, offering solutions to challenges associated with globalization and climate change. However, common features of plant biology complicate its application. Self-limiting methods provide acontrolled, reversible path forward.

## Full-text entities

- **Diseases:** death (MESH:D003643)
- **Chemicals:** TA (-)
- **Species:** Oryza sativa (Asian cultivated rice, species) [taxon 4530], Arabidopsis thaliana (mouse-ear cress, species) [taxon 3702], Homo sapiens (human, species) [taxon 9606], Drosophila melanogaster (fruit fly, species) [taxon 7227]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12027107/full.md

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Source: https://tomesphere.com/paper/PMC12027107