# Internet-Based Psycho-Physical Exercise Intervention Program in Mild-to-Moderate Depression: The Study Protocol of the SONRIE Randomized Controlled Trial

## TL;DR

The SONRIE study tests an online program combining exercise and therapy to reduce depression symptoms in adults.

## Contribution

This study introduces a novel internet-based combined intervention for mild-to-moderate depression.

## Key findings

- The study protocol outlines a 12-week online intervention with physical exercise and cognitive–behavioral therapy.
- Depression severity will be measured using the Beck Depression Inventory at multiple time points.
- The trial aims to assess the intervention's impact on depressive symptoms and its potential for clinical use.

## Abstract

The COVID-19 pandemic has intensified depression due to isolation and reduced physical activity, highlighting the need for accessible remote treatments. The SONRIE study evaluates the effectiveness of a 12-week online intervention combining physical exercise and internet-based cognitive–behavioral therapy on depressive symptoms in adults with mild-to-moderate depression. This randomized controlled trial involved 80 adults aged 25–65 years diagnosed with depression according to the ICD-10 criteria. Participants were randomized to an experimental group receiving the combined online intervention or to a control group receiving standard care. The primary outcome was the change in depression severity, assessed by the Beck Depression Inventory, with outcomes measured at baseline, immediately post-intervention, and after an 8-week follow-up phase. Statistical analyses include analysis of covariance to compare group changes over time, with effect sizes quantifying the intervention’s impact. The SONRIE study demonstrates a promising online approach for treating depression, with potential implications for clinical practice and public health strategies.