# Association Between Area-Level Deprivation and Cardio-Metabolic Risk Factors Among the Adult Population in Russia

**Authors:** Anastasia A. Zelenina, Svetlana A. Shalnova, Oksana M. Drapkina

PMC · DOI: 10.3390/ijerph22040594 · 2025-04-10

## TL;DR

This study finds that people in more deprived areas of Russia face higher risks of obesity, diabetes, and other cardio-metabolic issues.

## Contribution

The study is the first to examine area-level deprivation's impact on cardio-metabolic risk factors in Russia, considering individual characteristics.

## Key findings

- Economically deprived areas are linked to higher odds of obesity, chronic kidney disease, hyperuricemia, and diabetes.
- Environmental deprivation is associated with increased hypertension risk in both men and women.
- The associations remain significant even when analyzing men and women separately.

## Abstract

Background: Cardiovascular diseases have been the leading cause of death in the Russian population to date. Methods: Using generalized estimating equations, we examined the links of area-level socio-economic and environmental deprivation with cardiovascular disease risk factors in the adult population as a whole, as well as in men and women separately. Results: People living in more economically deprived areas had 61 percent higher odds of being obese (Q4: odds ratio (OR) 1.61; 95% confidence interval (CI): 1.20–2.16), 2.32 times higher odds of having chronic kidney disease (OR 2.32; 95% CI: 1.56–3.44), up to 57 percent higher odds of having hyperuricemia (OR 1.57; 95% CI: 1.31–1.88), and up to 80 percent higher odds of having diabetes mellitus (OR 1.80; 95% CI: 1.71–1.89), compared to those in the least deprived areas. Individuals living in the most environmentally deprived areas were associated with higher odds of hypertension (OR 1.37; 95% CI: 1.19–1.57) and these associations persisted for both when considering men (OR 1.38; 95% CI: 1.19–1.61) and women (OR 1.37; 95% CI: 1.14–1.65) separately. Conclusions: This is the first study to examine the relationship of area characteristics with cardio-metabolic risk factors such as elevated blood pressure and prediabetes, taking into account individual characteristics among the Russian population.

## Linked entities

- **Diseases:** chronic kidney disease (MONDO:0005300), hyperuricemia (MONDO:0002144), diabetes mellitus (MONDO:0005015)

## Full-text entities

- **Diseases:** prediabetes (MESH:D011236), diabetes mellitus (MESH:D003920), elevated blood (MESH:D006402), chronic kidney disease (MESH:D051436), obese (MESH:D009765), hypertension (MESH:D006973), death (MESH:D003643), Cardiovascular diseases (MESH:D002318), hyperuricemia (MESH:D033461)
- **Species:** Homo sapiens (human, species) [taxon 9606]

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Source: https://tomesphere.com/paper/PMC12026931