# Evaluating the Role of School-Based Physical Activity in Mitigating Cardiometabolic Risk Factors in Children and Adolescents with Overweight or Obesity: A Systematic Review and Meta-Analysis

**Authors:** Dingmeng Mao, Bowen Li

PMC · DOI: 10.3390/children12040439 · Children · 2025-03-29

## TL;DR

School-based physical activity can reduce certain cardiometabolic risks in overweight or obese children and teens, but not all health indicators improve.

## Contribution

This study provides a meta-analysis showing specific cardiometabolic benefits of school-based physical activity for overweight or obese youth.

## Key findings

- School-based PA significantly reduces body fat, diastolic blood pressure, and triglycerides in overweight or obese youth.
- Interventions lasting 6 weeks or more, twice a week or more, show the most significant cardiometabolic improvements.
- No significant changes were observed in BMI, waist measurements, or cholesterol levels.

## Abstract

Background: Overweight or obese children and adolescents have a higher risk of developing cardiometabolic health problems compared with their healthy-weight peers, which are likely to progress to cardiovascular disease and are associated with a range of negative impacts. Objectives: To evaluate the effects of school-based physical activity (PA) interventions on cardiometabolic risk factors in children and adolescents with overweight or obesity. Method: A search of online databases was conducted to identify relevant studies up to 31 January 2025. Results: Eleven studies were included, involving 963 participants aged 7 to 18 years. School-based PA interventions have a significant effect size (ES) in reducing body fat percentage (ES = −0.43, p < 0.01), diastolic blood pressure (ES = −0.27, p < 0.05), triglycerides (ES = −0.38, p < 0.01), fasting blood glucose (ES = −0.60, p < 0.01), blood insulin (ES = −0.62, p < 0.01), and homeostatic model assessment-insulin resistance (ES = −0.58, p < 0.01) in overweight or obese students. However, no significant improvements were observed in body mass index, body mass index z-score, waist circumference, waist-to-height ratio, maximal oxygen consumption, systolic blood pressure, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and total cholesterol. Conclusion: School-based PA interventions lasting 6 weeks longer, twice a week or more, can significantly mitigate some cardiometabolic risks of overweight or obese children and adolescents. Effective, targeted PA programs should be considered in the school setting to promote the cardiometabolic health of this vulnerable group.

## Linked entities

- **Diseases:** cardiovascular disease (MONDO:0004995)

## Full-text entities

- **Diseases:** Overweight (MESH:D050177), cardiovascular disease (MESH:D002318), Obesity (MESH:D009765), insulin resistance (MESH:D007333), cardiometabolic health problems (MESH:D024821)
- **Chemicals:** triglycerides (MESH:D014280), insulin (MESH:D007328), glucose (MESH:D005947), oxygen (MESH:D010100), cholesterol (MESH:D002784)

## Full text

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## Figures

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## References

62 references — full list in the complete paper: https://tomesphere.com/paper/PMC12025731/full.md

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Source: https://tomesphere.com/paper/PMC12025731