# A Combined Approach Using Strip Grafts and Xenogenic Dermal Matrix for Peri-Implant Keratinized Mucosa Augmentation in the Mandible: A Case Series

**Authors:** Xinda Li, Dániel Palkovics, Péter Windisch, Željka Perić Kačarević, Attila Horváth

PMC · DOI: 10.3390/biomedicines13040806 · Biomedicines · 2025-03-27

## TL;DR

This study explores a new surgical method combining strip grafts and xenogenic dermal matrix to improve dental implant health by increasing keratinized mucosa in the mandible.

## Contribution

A novel combined surgical approach using autogenous strip grafts and xenogenic dermal matrix for mandibular peri-implant mucosa augmentation is introduced.

## Key findings

- The combined approach significantly increased peri-implant keratinized mucosa width and thickness over 12 months.
- Graft shrinkage was observed but remained manageable, with stable results by 12 months.
- Clinical improvements were statistically significant compared to baseline measurements.

## Abstract

Background: Ensuring a minimum peri-implant keratinized mucosa width (PIKM-W) is critical for maintaining dental implant health, as inadequate PIKM-W is associated with increased risks of plaque accumulation, mucosal inflammation, and peri-implantitis. While epithelialized connective tissue grafts (ECTGs) are considered the gold standard for soft tissue augmentation, they often lead to significant patient morbidity. Xenogeneic dermal matrices (XDMs) offer a less invasive alternative, but are prone to shrinkage, particularly in the mandible. The aim of this study was to evaluate a new surgical method to overcome these limitations with the combination of a narrow band of ECTG (autogenous strip graft, ASG) and an XDM to augment the PIKM-W in the posterior mandible. Methods: Twelve patients with a PIKM-W of less than 2 mm in the mandible underwent peri-implant soft tissue augmentation using this combined approach. Changes in the PIKM-W were measured preoperatively; immediately postoperatively; and at 1, 3, 6, 9, and 12 months. Graft remodeling (shrinkage or contraction) and PIKM thickness (PIKM-T) were also evaluated over time. Results: Preoperatively, the mean PIKM-W was 0.39 ± 0.40 mm and the PIKM-T was 1.36 ± 0.43 mm. At 6 months, the mean PIKM-W was 4.93 ± 0.98 mm and the PIKM-T was 2.88 ± 0.80 mm, with shrinkage of 39.2 ± 14.1%. By 12 months, the mean PIKM-W stabilized at 4.58 ± 1.28 mm and the PIKM-T stabilized at 2.83 ± 0.65 mm, with shrinkage of 42.2% ± 16.8%. Conclusions: There were statistically significant differences in clinical parameters between the baseline and 6 and 12 months (p < 0.05). This technique demonstrated the potential for stable augmentation of PIKM-W and PIKM-T over time, with manageable shrinkage. However, further studies with larger sample sizes are needed to confirm its clinical efficacy as an alternative for mandibular keratinized mucosa augmentation around implants.

## Full-text entities

- **Diseases:** mucosal inflammation (MESH:D007249), peri-implantitis (MESH:D057873)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

33 references — full list in the complete paper: https://tomesphere.com/paper/PMC12025105/full.md

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Source: https://tomesphere.com/paper/PMC12025105