# Paediatric Systemic Lupus Erythematosus with chronic diarrhea as an initial presentation

**Authors:** Ali Abdur Rahman, Asfand Tariq

PMC · DOI: 10.12669/pjms.41.4.10235 · Pakistan Journal of Medical Sciences · 2025-04-01

## TL;DR

A rare case of lupus in a child presented with chronic diarrhea, highlighting the importance of early diagnosis to avoid serious complications.

## Contribution

This case report highlights the rare initial presentation of lupus enteritis in a child with chronic diarrhea.

## Key findings

- Lupus enteritis can present with chronic diarrhea as the sole initial symptom in children.
- Early diagnosis and treatment lead to a good prognosis in lupus enteritis.
- LE is rare but can cause severe complications like intestinal bleeding and perforation if undiagnosed.

## Abstract

Lupus enteritis (LE) is a rare manifestation of Childhood Systemic lupus erythematosus (cSLE). The presentation is non-specific i.e loose motions, non-specific abdominal pain, nausea and vomiting. Presenting as a sole initial clinical finding in the absence of other common findings of systemic lupus erythematosus (SLE) makes the diagnosis challenging. After a detailed workup, our patient was diagnosed with LE based on history, physical and laboratory investigations and responded well with initial management. Our report emphasizes the rarity of LE and the significance of its prevalence in the childhood population due to increased morbidity, mortality and complications such as intestinal bleeding, perforation and infarction. With early diagnosis and treatment, there is an excellent prognosis.

## Linked entities

- **Diseases:** Systemic lupus erythematosus (MONDO:0007915)

## Full-text entities

- **Diseases:** perforation (MESH:D057112), SLE (MESH:D008180), infarction (MESH:D007238), vomiting (MESH:D014839), nausea (MESH:D009325), chronic diarrhea (MESH:D003967), LE (MESH:D004751), bleeding (MESH:D006470), abdominal pain (MESH:D015746)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12022599/full.md

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Source: https://tomesphere.com/paper/PMC12022599