# EIT Observed Hypoxemia Caused by V/Q Mismatch During One‐Lung Ventilation With Indocyanine Green Inhalation: A Report of Two Cases

**Authors:** Xiaoyan Li, Maokun Li, Jian Zhou, Yi Feng, Ke Zhang, Haiyan Xu, Zhenfan Wang, Xue Tian

PMC · DOI: 10.1002/rcr2.70154 · Respirology Case Reports · 2025-04-24

## TL;DR

This case report shows how Electrical Impedance Tomography (EIT) helps identify hypoxemia during one-lung ventilation by tracking ventilation-perfusion mismatches.

## Contribution

The study demonstrates EIT's utility in real-time monitoring of V/Q mismatch during nebulization under one-lung ventilation.

## Key findings

- EIT revealed individual differences in pulmonary blood flow redistribution leading to hypoxemia.
- The lateral decubitus position worsened hypoxemia when the ventilated lung was in the upper position.
- EIT provided actionable insights for managing hypoxemia during surgical procedures.

## Abstract

Nebulization under one‐lung ventilation (OLV) can facilitate precise localisation of pulmonary tumours and assist in surgical manipulation. However, hypoxaemia during the nebulization process remains a challenging issue. In this report, we present two cases monitored using Electrical Impedance Tomography (EIT), where individual differences in pulmonary blood flow redistribution contributed to hypoxaemia. This phenomenon was further exacerbated in the lateral decubitus position with the ventilated lung in the upper position. EIT provided real‐time insights into ventilation‐perfusion (V/Q) distribution, offering valuable guidance for managing hypoxaemia during nebulization and surgery under OLV.

In this report, we present two cases monitored using Electrical Impedance Tomography (EIT), where individual differences in pulmonary blood flow redistribution contributed to hypoxemia. This phenomenon was further exacerbated in the lateral decubitus position with the ventilated lung in the upper position. EIT provided real‐time insights into ventilation‐perfusion (V/Q) distribution, offering valuable guidance for managing hypoxemia during nebulisation and surgery under OLV.

## Full-text entities

- **Diseases:** Hypoxemia (MESH:D000860), pulmonary tumours (MESH:D008175)
- **Chemicals:** Indocyanine Green (MESH:D007208)

## Full text

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## Figures

5 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12022226/full.md

## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC12022226/full.md

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Source: https://tomesphere.com/paper/PMC12022226