# Case Report: A case of membranous nephropathy associated with primary Sjögren’s syndrome treated with telitacicept

## TL;DR

A patient with kidney disease linked to Sjögren’s syndrome improved after treatment with methylprednisolone and telitacicept.

## Contribution

This case report presents a successful treatment approach for membranous nephropathy associated with primary Sjögren’s syndrome.

## Key findings

- A patient with MN associated with pSS showed improvement after treatment with methylprednisolone and telitacicept.
- Current unified treatment guidelines for MN associated with pSS are lacking, highlighting the need for further research.

## Abstract

Primary Sjögren’s syndrome (pSS) is an autoimmune disease that often affects the exocrine glands. However, pSS can also affect the kidneys, most commonly involving the kidney interstitium. Recent studies have demonstrated that some membranous nephropathy (MN) cases are associated with Sjögren’s syndrome. However, unified recommendations for selecting immunosuppressive agents for treating MN associated with pSS are currently lacking. In the case reported herein, a patient with MN associated with pSS experienced improvement following methylprednisolone and telitacicept treatment.