# Perioperative management of caesarean section for a pregnant woman with Sjögren's disease and pulmonary embolism: a case report

**Authors:** Fanghao Liu, Xiaohui Wang, Shu Yuan, Lin Xu, Kaiyue Shan, Longfei Wang, Jianting Huang, Qiang Zheng

PMC · DOI: 10.3389/fcvm.2025.1467309 · 2025-04-11

## TL;DR

A pregnant woman with Sjögren's disease and pulmonary embolism required careful management during a caesarean section to ensure the health of both mother and baby.

## Contribution

This case report highlights the rare and complex scenario of Sjögren's disease complicated by pulmonary embolism during pregnancy and its successful perioperative management.

## Key findings

- A 40-year-old pregnant woman with Sjögren's disease developed pulmonary embolism during the perioperative period of a caesarean section.
- Multidisciplinary care including anticoagulation and vena cava filter implantation led to recovery of both mother and neonate.
- Early identification and comprehensive monitoring are crucial for managing Sjögren's disease complicated by pulmonary embolism during pregnancy.

## Abstract

Sjögren's disease (SjD) is a chronic inflammatory autoimmune disease with significant female predominance, characterised by lymphocyte proliferation and progressive damage to exocrine glands. The complexity of the condition of women with SjD and the incidence of complications substantially increase during pregnancy, which undoubtedly has consequences on both maternal health and neonatal outcomes. Pulmonary embolism (PE) is associated with increased perinatal mortality. However, PE has rarely been reported in pregnant women with SjD.

A 40-year-old pregnant woman was diagnosed as having SjD. During admission, she experienced chest tightness and suffocation and was scheduled for caesarean section under combined spinal-epidural anaesthesia because of sustained low oxygen saturation and foetal distress. Postoperative pulmonary artery computed tomography angiography confirmed that the patient had developed a pulmonary embolism during the perioperative period. After multidisciplinary consultation, the patient underwent inferior vena cava filter implantation, anticoagulation, oxygen therapy, and anti-infection therapy; both the mother and neonate recovered and were discharged.

Early identification and comprehensive perioperative monitoring during the prenatal period are vital in patients with SjD complicated by PE.

## Linked entities

- **Diseases:** pulmonary embolism (MONDO:0005279)

## Full-text entities

- **Diseases:** SjD (MESH:D012859), inflammatory autoimmune disease (MESH:D001327), infection (MESH:D007239), PE (MESH:D011655), foetal distress (MESH:D012128)
- **Chemicals:** oxygen (MESH:D010100)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12021838/full.md

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Source: https://tomesphere.com/paper/PMC12021838